Beatriz García Pinel, PhD in Biomedicine. Postdoctoral Research Associate

beatriz.garcía.pinel@usc.es

In 2021, I obtained my Ph.D. in Biomedicine, focused on the use of nanoparticles to improve delivery and reduce side effects of first-line treatments used in colorectal cancer. In early 2022 I joined the Immunity and Small Molecules Lab as a Postdoctoral Research Associate.

Timeline


2022 - present Postdoctoral Researcher. Centre for Research in Molecular Medicine and Chronic Diseases (CiMUS), University of Santiago de Compostela, Spain.

2017 - 2021 Predoctoral researcher in Biomedicine at University of Granada. Granada, Andalucia, Spain. FPU Grant.

2016 - 2017 MSc student. In Regenerative Biomedicine at University of Granada. Granada, Andalucia, Spain.

2012 - 2016 BSc student. in Biotechnology at University of Cádiz. Cádiz, Andalucia, Spain.

Selected publications (last 5 years)


  1. Prieto-Díaz, R., González-Gómez, M., Fojo-Carballo, H., Azuaje, J., El Maatougui, A., Majellaro, M., Loza, M. I., Brea, J., Fernández-Dueñas, V., Paleo, M. R., Díaz-Holguín, A., Garcia-Pinel, B., Mallo-Abreu, A., Estévez, J. C., Andújar-Arias, A., García-Mera, X., Gomez-Tourino, I., Ciruela, F., Salas, C. O., Gutiérrez-de-Terán, H., … Sotelo, E. (2022). Exploring the Effect of Halogenation in a Series of Potent and Selective A2B Adenosine Receptor Antagonists. Journal of medicinal chemistry. 10.1021/acs.jmedchem.2c01768. Advance online publication. https://doi.org/10.1021/acs.jmedchem.2c01768

  2. Alvear-Jiménez, A., Zabala Gutierrez, I., Shen, Y., Villaverde, G., Lozano-Chamizo, L., Guardia, P., Tinoco, M., Garcia-Pinel, B., Prados, J., Melguizo, C., López-Romero, M., Jaque, D., Filice, M., & Contreras-Cáceres, R. Electrospraying as a Technique for the Controlled Synthesis of Biocompatible PLGA@Ag2S and PLGA@Ag2S@SPION Nanocarriers with Drug Release Capability. Pharmaceutics 2022, 14(1), 214. https://doi.org/10.3390/pharmaceutics14010214

  3. Ortíz, R.; Quiñonero, F.; García-Pinel, B.; Fuel, M.; Mesas, C.; Cabeza, L.; Melguizo, C.; Prados, J. Nanomedicine to Overcome Multidrug Resistance Mechanisms in Colon and Pancreatic Cancer: Recent Progress. Cancers 2021, 13, 2058, doi:10.3390/cancers13092058.

  4. Rama, A.R.; Perazzoli, G.; Cabeza, L.; Mesas, C.; Quiñonero, F.; García-Pinel, B.; Vélez, C. Novel MicroRNA Sponges to Specifically Modulate Gene Expression in Colon Cancer Cells. Nucleic Acid Ther. 2020, 30, 325–334, doi:10.1089/nat.2020.0861.

  5. García-Pinel, B.; Porras-Alcalá, C.; Cabeza, L.; Ortiz, R.; Prados, J.; Melguizo, C.; Cheng-Sánchez, I.; López-Romero, J.M.; Sarabia, F. Bengamide Analogues Show A Potent Antitumor Activity against Colon Cancer Cells: A Preliminary Study. Mar. Drugs 2020, 18, 240, doi:10.3390/md18050240.

  6. Garcia-Pinel, B.; Jabalera, Y.; Ortiz, R.; Cabeza, L.; Jimenez-Lopez, C.; Melguizo, C.; Prados, J. Biomimetic Magnetoliposomes as Oxaliplatin Nanocarriers: In Vitro Study for Potential Application in Colon Cancer. Pharmaceutics 2020, 12, doi:10.3390/pharmaceutics12060589.

  7. Garcia-Pinel, B.; Ortega-Rodríguez, A.; Porras-Alcalá, C.; Cabeza, L.; Contreras-Cáceres, R.; Ortiz, R.; Díaz, A.; Moscoso, A.; Sarabia, F.; Prados, J.; et al. Magnetically Active PNIPAM Nanosystems as Temperature-Sensitive Biocompatible Structures for Controlled Drug Delivery. Artif. Cells Nanomedicine Biotechnol. 2020, 48, 1022–1035, doi:10.1080/21691401.2020.1773488.

  8. Cabeza-Montilla, Laura; Jiménez -Luna, Cristina; García-Pinel, Beatriz; Mesas, Cristina; Quiñonero F; Perazzoli, Gloria. Verapamil modulates p-glycoprotein expression in resistant colon cancer cells. Actas de Investigación Oncológica. 2020, 3, ISSN 2695-3781.

  9. Ortiz, R.; Cabeza, L.; Perazzoli, G.; Jimenez-Lopez, J.; García-Pinel, B.; Melguizo, C.; Prados, J. Nanoformulations for Glioblastoma Multiforme: A New Hope for Treatment. Future Med. Chem. 2019, 11, 2459–2480, doi:10.4155/fmc-2018-0521.

  10. Jabalera, Y.; Garcia-Pinel, B.; Ortiz, R.; Iglesias, G.; Cabeza, L.; Prados, J.; Jimenez-Lopez, C.; Melguizo, C. Oxaliplatin-Biomimetic Magnetic Nanoparticle Assemblies for Colon Cancer-Targeted Chemotherapy: An In Vitro Study. Pharmaceutics 2019, 11, E395, doi:10.3390/pharmaceutics11080395.

  11. García-Pinel, B.; Porras-Alcalá, C.; Ortega-Rodríguez, A.; Sarabia, F.; Prados, J.; Melguizo, C.; López-Romero, J.M. Lipid-Based Nanoparticles: Application and Recent Advances in Cancer Treatment. Nanomater. Basel Switz. 2019, 9, doi:10.3390/nano9040638.